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1996-03-09
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Document 0200
DOCN M9650200
TI Testing of saliva and serum for HIV in high-risk populations. Ad Hoc
Group for the Comparative Saliva and Serum Study.
DT 9605
AU Vall Mayans M; Casabona J; Rabella N; De Miniac D; AIDS Programme,
Department of Health, Generalitat de Catalunya,; Barcelona, Spain.
SO Eur J Clin Microbiol Infect Dis. 1995 Aug;14(8):710-3. Unique Identifier
: AIDSLINE MED/96089508
AB Paired samples of saliva and serum from 286 high-risk subjects were
tested for HIV using two commercial enzyme immunoassays following the
same WHO testing strategy supplemented with a Western blot technique.
Agreement between HIV testing in both sample types was 98.9% (95%
confidence interval: 97.7-100). The sensitivity of an EIA (Wellcozyme
GACELISA) alone for saliva was 100% (133/133) and the specificity 98.7%
(151/153). These results support previous data showing that in some
situations saliva might be an effective alternative to serum for HIV
testing.
DE Adult AIDS Serodiagnosis/*METHODS Blotting, Western Confidence
Intervals Female Human HIV Antibodies/*ANALYSIS HIV
Infections/*DIAGNOSIS HIV Seroprevalence Immunoenzyme Techniques Male
Saliva/*VIROLOGY Sensitivity and Specificity JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).